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Materials and methods Animal experiments and estrogen treatment in ovariectomized rats Experimentally naive, 812-week-old female Long-Evans rats, both intact and ovariectomized (OVX), were obtained from Charles River Laboratories (Houston, TX)

In particular, the Lys8, Trp207 and Lys210 residues showed structural differences from their corresponding residues compared with the oxidized and GSH-bound structures and rearrangement of these residues is related to the movements necessary for the interactions involved in AsA binding (Fig