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Mathialagan et al., 2018)

Moreover, in a xenograft mammary 4T1 tumor model, it has been demonstrated that the concurrent administration of BAPN and the enzyme-responsive drug (NQO1-SN38), designed to target breast tumors with the topoisomerase I inhibitor SN38, results in a cooperative reduction in tumor growth [100]

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PT-141 / 10mg PT-141, also known as bremelanotide, is a synthetic melanocortin-receptor peptide studied for its relevance to melanocortin signaling, receptor-binding behavior, central neuropeptide pathway research, and cellular communication models