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When to Consider Alternative GLP-1 Options for Mood Stability If depression emerges on semaglutide, switching to tirzepatide (which activates both GLP-1 and GIP receptors) may offer a different neurochemical profile that feels better tolerated

We set qualifying patients a weight loss target for 12 weeks after they reach their maintenance dose of their Wegovy treatment, typically this is a minimum of 5% of their starting weight

Tirzepatide works similarly on the GLP-1 receptor, but also binds to the GIP receptor as well

Seek urgent medical attention for severe persistent vomiting, signs of dehydration, severe abdominal pain, or symptoms suggesting pancreatitis whilst taking Victoza