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ACS Cent Sci 7:980989 Horonchik L, Wessling-Resnick M (2008) The small-molecule iron transport inhibitor ferristatin/NSC306711 promotes degradation of the transferrin receptor

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If youre considering adding coffee enemas into a broader detox or gut-healing plan, working with a qualified functional medicine provider ensures youre doing it safely and effectively.These individuals should not perform coffee enemas: Those with inflammatory bowel disease (Crohns, UC) Severe hemorrhoids Kidney disease Heart rhythm disorders Pregnant individuals Those sensitive to caffeine Consult a licensed medical provider before starting any detox or gastrointestinal protocol