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For example, in a rat sciatic nerve injury model, Melanotan 2 significantly enhanced the recovery of sensory function

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Baseline PD-L1 surface expression in both Myc-CaP and 22Rv1 prostate cancer cells was low, and IGF-1 stimulation did not result in a clear increase in surface PD-L1 levels in 22Rv1 cells (Supplementary Figure S5B-C)