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One of the mechanisms by which senescent cells escape from the immune response is made through the overexpression of the histocompatibility antigen alpha chain E (HLA-E) that bind to NKG2A, an inhibitor receptor expressed on Natural Killer cells (NK) 54 and CD8 + T cells, leading to the inhibition of SnCs recognition

Medications like methylphenidate, which primarily target dopamine and norepinephrine, are effective in improving symptoms in around 60-70% of patients

The concentration is high enough to keep injection volumes reasonable while making dose calculations straightforward

The differences between the genotypic and allelic frequencies of the study groups were compared by the Pearson Chi-square test, and odds ratios (OR) were established with a 95% confidence interval (95% CI)