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Vitamin C: Helps lifeless, dull skin find its own strength, leaving it clean and clear

10.1371/journal.pone.0045825 PLoS ONE 108 XuQ.JiangY.YinY.LiQ.HeJ.JingY.et al (2013)

In addition, NAD + production by the NNT enhance SIRT3-mediated deacetylation and loss of NAD + -dependent deacetylase SIRT3 increases the acetylation of IDH2 at K413 and decreases its enzymatic activity by reducing dimerization, thus regulates mitochondrial redox status and promotes cell tumorigenesis in luminal B breast cancer, 137 and B cell malignancies