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Aside from weight gain, the menopause transition is associated with changes in body composition including an increase in fat mass, a decrease in lean mass, and an increase in abdominal adiposity
Tolerability, ease of administration, minimal monitoring requirements and cost are also important determinants of acceptability, and preventive advantage for individuals with impaired glucose tolerance would be very desirable
Clinicians are now asking an important question: could lower-cost alternatives fundamentally reshape diabetes care
This requires reducing caffeine, ideally, and restoring electrolytes
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