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Anti-obesity medications have established themselves in the publics mind as powerful tools for shrinking waistlines and have generated extraordinary levels of excitement, however, they are now at the forefront of a wider therapeutic revolution
Various biomarkers are not all equivalent and have differential value for disease diagnosis and drug development
A permanent reduction of expression/activity of GluN2B-subunit-containing NMDAR has been found to counteract LTP impairment in the hippocampal CA1 area of the AD mouse model mAPP (Rammes et al., 2017)
Large-scale trials are required [51]
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