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Among the tested formulations, PNP-1-10-0.05 Sema-1.8 mg/mL exhibited the most favorable safety profile across all evaluated tissues, while PNP-1-10-0.05 TZP-4.5 mg/mL, though eliciting a modest increase in localized tissue response, remained substantially more biocompatible than daily bolus TZP

DECLARATIONS Acknowledgments We are grateful to our colleagues involved in the present PAS research, including Dr

[DOI] [PMC free article] [PubMed] 14.Clemente M.G., Mandato C., Poeta M., Vajro P