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Med.1987;110:9196

June 15, 2020, 18:34 UTC

When amino acids reach the small intestine, they directly trigger L cells to release GLP-1 through nutrient-sensing mechanisms involving the calcium-sensing receptor (CaSR) and peptide transporter 1 (PEPT1)

[52], [53] Further complicating this is the fact that many providers perceive NAFLD as a benign entity and subsequently, many patients with a high likelihood of NAFLD do not complete formal evaluation to confirm the diagnosis and are not subsequently referred to specialists who are involved in clinical trial recruitment.[54], [55] Primary care physicians, endocrinologists, gynaecologists, cardiologists and to some extent gastroenterologists lack awareness of NAFLD/NASH progression and its associated risk factors