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August 2025: Teva Pharmaceuticals launched the first FDA-approved generic of Saxenda (liraglutide injection) in the United States, expanding lower-cost options for prescribers

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This finding highlights not only the key role that mitochondrial metabolism has in modulating response and resistance to TS inhibitors, but the wider opportunity afforded to enhance TS inhibitor-mediated anti-cancer effects by targeting mitochondrial metabolism using metformin or other compounds with similar mitochondrial impact