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Trials are investigating obesity, overweight with weight-related conditions, type 2 diabetes, knee osteoarthritis pain, moderate-to-severe obstructive sleep apnea, chronic low back pain, cardiovascular and renal outcomes, and metabolic dysfunction-associated steatotic liver disease

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Future research in PD is increasingly focused on identifying specific microbial metabolites or strains that could be targeted to slow neurodegeneration (for instance, boosting SCFA producers or inhibiting bacterial enzymes that interfere with host molecules)

There will be above-average responders and there will be nonresponders