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5.2 Immunotherapies Recently, vaccine strategies have exploited the haem-dependant NTHi pathogenic mechanisms by incorporating the surface haemoprotein receptor, PE as a vaccine antigen

[13] [14] Melanonychia linked with syndromes, such as Peutz-Jeghers, Touraine, and Laugier-Hunziker, usually affects numerous digits and is accompanied by mucosal pigmented macules including the lips and oral cavity