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Some studies propose potentially cardioprotective and renoprotective actions, while others highlight an enhanced vulnerability of some DPP-4 inhibitors to cause heart failure

EVK, H., et al., Exposure to continuous darkness ameliorates gastric and colonic inflammation in the rat: Both receptor and non-receptor-mediated processes

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Abstract Steroidal 5-reductase is a system of NADPH dependent enzyme that catalyzes the irreversible conversion of 43-ketosteroid precursor (testosterone) to its corresponding 5-reduced metabolite (dihydrotestosterone)