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In other words, your metabolism has changed

the rationale is based on the fact that improved glycemia restores sensitivity to GIP [14, 16] and peptide engineering enables the design of hybrid ligands exhibiting dual agonism, as proved in experimental studies [19]

doi: 10.2337/dc22-1148 69 NauckMAPetrieJRSestiGMannucciECourrgesJPLindegaardMLet al

During the dose escalation phasespanning 16 weeks for Wegovy's weight management formulationappetite suppression generally intensifies as the dosage increases