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Description

The primary risk is rubber particulate introduction from forcing a thin 29-31 gauge needle through a thick rubber stopper, which creates microscopic coring (rubber fragments sheared into the vial)

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A.KuhlI.et al (2015)

According to the voltage-driven promotion mechanism of NPT4L and its location on the proximal membrane of the proximal tubule, deeming NPT4 is the main channel for excretion of drugs and UA (Jutabha et al., 2010)