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Gaetano Morelli, Chief Medical Officer at Altasciences

GLUTag cell experiments were performed following the same protocol as for NCI H716 cells but with seeding of the cells directly into the 96-well plates, with no need for Matrigel coating due to their adherent nature

Microsomal GSTs are membrane-associated proteins in eicosanoid and glutathione metabolism (6,7)

It sheds light on the emerging knowledge regarding the peptides, their specific receptors on brain endothelial cells, the selection of drug payloads, the design of DSIP-CBBBP, mechanisms of brain entry, and the efficiency of delivery to the brain ( On the other hand, the lack of a significant anxiolytic effect with GABA treatment raises questions about its bioavailability or receptor interactions in the specific context of the EPM test, possibly due to differences in the route of administration, dosage, or the animal models specific pathology