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For omega-3s, choose a reputable source of fish oil or algae-based supplements that provide adequate amounts of EPA and DHA

High Fat Diet Dysregulates Hypothalamic-Pituitary Axis Gene Expression Levels which are Differentially Rescued by EPA and DHA Ethyl Esters

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This mechanism is illustrated in Figure 14, highlighting how SFNs interaction with Keap1 leads to Nrf2 activation and subsequent cellular protective responses [106,107]