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The administration of valproate to obese patients results in an increase in serum leptin levels compared to non-obese patients [91], but there is no answer yet as to which VPA metabolites induce this ADR

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doi: 10.1111/dom.12084 23 ArslanianSAHannonTZeitlerPChaoLCBoucher-BerryCBarrientos-PrezMet al