glp 1 in heart failure

glp 1 in heart failure GLP-1 receptor agonists and myocardial metabolism atrial fibrillation Mechanisms of GLP-1 Receptor Agonists

Name: glp 1 in heart failure GLP-1 receptor agonists and myocardial metabolism atrial fibrillation Mechanisms of GLP-1 Receptor Agonists
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Description

We previously showed that both GLP-1 and GLP-1(936) cause the release of guanosine 3,5-cyclic guanosine monophosphate (cGMP) and cAMP in coronary effluents of isolated perfused hearts from WT and Glp1r / mice (4), thus directly implicating GLP-1 and its DPP-4generated metabolite in GLP-1Rindependent production of cAMP (4, 21)

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