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The potential biomarkers analyzed included DNA polymorphisms, gene expression levels quantified as mRNA and proteins, and metabolites, as well as methylation markers, microRNAs, and malignant primary circulating prostate cells

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After a single intravenous (IV) administration, single intramuscular (IM) administrations at three doses in successive increments along with repeated IM administrations, the elimination half-life (t 1/2 ) of prototype BPC157 was less than 30 min, and BPC157 showed linear pharmacokinetic characteristics in rats and beagle dogs at all doses