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Borner MM, Schoffski P, de Wit R, Caponigro F, Comella G, Sulkes A et al (2002) Patient preference and pharmacokinetics of oral modulated UFT versus intravenous fluorouracil and leucovorin: a randomised crossover trial in advanced colorectal cancer

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This mechanism can be classified as direct physical antagonism and chemical antagonism with soluble molecules [25, 159]