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Empagliflozin tablets (Jardiance 10 mg, Boehringer Ingelheim, Germany) were disintegrated and suspended in 0.5% carboxymethylcellulose (CMC)

Yang C, Hou X, Ma X, et al

Some individuals might experience gastrointestinal disturbances, such as nausea or diarrhea, primarily due to the bodys reaction to the increased flow of bile and fat metabolism

In CCK1R null mice the alteration of meal patterns is more marked when ingesting a high fat diet: fat seems to be a potent inhibitor of food intake via CCK release.58 Nutrients and PYY release Nutrients stimulate PYY release within 30min from ingestion of a meal, usually reaching a maximum within 60min59 and proportionally to calorie intake