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Orforglipron (LY3502970), a novel, oral non-peptide glucagon-like peptide-1 receptor agonist: A Phase 1b, multicentre, blinded, placebo-controlled, randomized, multiple-ascending-dose study in people with type 2 diabetes

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Glucagon receptor activation the novel third arm is associated in published research models with increased hepatic lipid oxidation, raised resting energy expenditure, and accelerated reduction of hepatic triglyceride content

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