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In pregnant female rats given subcutaneous doses of 0.1, 0.25 and 1.0 mg/kg/day liraglutide from gestation day 6 through weaning or termination of nursing on lactation day 24, estimated systemic exposures were 0.8-, 3-, and 11-times human exposure at the MRHD of 1.8 mg/day, based on plasma AUC

Studies suggest that there are many causes of gynecomastia, including multiple different prescription drugs ( As mentioned, when gynecomastia appears in bodybuilders, its typically caused by the use of anabolic steroids, such as exogenous testosterone derivatives

The AEs reported in this analysis were the most frequently reported AEs (proportion of participants in the safety analysis set with one event or more) according to system organ class in the semaglutide arm of each pooled dataset