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ChIPqPCR was used to evaluate histone lactylation at the promoters of profibrotic genes in TGF-1 + IL-1- or exogenous lactate-stimulated lung fibroblasts

This study also confirmed the wound-healing ability of graphene oxide (GO)/metformin (Met) hydrogels in vivo, indicating their wound healing-promoting effect in diabetic wounds [154]

174 CRTC1 upon dephosphorylation due to neuronal activity is translocated to nucleus, where it binds to the transcriptional complexome in CRE/TATA promoters to promote neuronal-activity dependent transcription