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Regulatory status will remain contingent on new data and prevailing evidence standards, as well as the absence of approved therapeutic uses to date

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Although the thioredoxin and glutaredoxin systems are both found in the chloroplast stroma (Rouhier et al., in vitro redox-midpoint of GCL (Hicks et al., Plant Glutathione Synthetases: Structure, Function, and Product Diversity In the second step of glutathione synthesis, GS catalyzes the ATP-dependent addition of glycine to -glutamylcysteine (Figure 1)

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