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The conjugate delivers about seven thousand times fewer lanifibranor molecules per kilogram of mouse, per day, than the dose required to produce the same nuclear-receptor effects when lanifibranor is given as a standalone drug.) If the conjugate were merely diluted lanifibranor, this dose would do nothing

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Male patients predominantly experienced AEs within the initial 30-day window following treatment initiation, whereas female patients exhibited a delayed onset pattern, with the majority of AEs emerging after 360 days of continuous therapy