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Low glutathione levels have been associated with: Aging Chronic disease Neurodegenerative conditions Increased oxidative stress Research published in PubMed-indexed journals shows that glutathione depletion is linked to impaired cellular function and increased susceptibility to oxidative damage (Wu et al., J Nutr, 2004)

For 2D embedding, the expression matrix was subset to the 2000 most highly variable genes (sc.pp.highly_variable_genes, flavor seurat)