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Published data1 indicate that acetylcysteine is not mutagenic in the Ames test, both with and without metabolic activation
F., Kamisah, Y., & Kumar, J
One possible explanation for the similar effects on weight loss observed with both GIPR agonism and antagonism might be that chronic pharmacological GIPR activation induces functional antagonism in a subset of neurons through receptor desensitization, as seen in adipocytes, isolated pancreatic islets and mouse neuroblastoma Neuro2a cells 36,37
10.1001/jama.2016.9400 18
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