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Given that IGF1 and cognate receptor are expressed in germ cells, LCs and Sertoli cells [49], intratesticular IGF1 could regulate various aspects of testicular function in both autocrine and paracrine manners

[ 10] The subsequent hydrolysis of GPC into glycerol 3-phosphate and choline is catalyzed by glycerophosphodiesterase (GDE) according to cellular needs

47 These findings offer promising directions for exploring KARs as potential drug targets to address CNS disorders and pave the way for further research in understanding the complexities of KAR biology and its implications in neuronal communication and modulation

Considerations: May cause side effects such as elevated heart rate, insomnia, anxiety, or dry mouth