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To elucidate the mechanism behind the beneficial effects of glutathione, further studies that examine the incorporation of orally administrated glutathione into the liver and the effects on the host redox system using stable isotope-labeled glutathione and animal models are required

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Finally, it is worth mentioning the new glutamate-serine-glycine (GSG) index which, combining three amino acids involved in glutathione synthesis, provides a good assessment of NAFLD severity and allows the discrimination of liver fibrosis (64)

Jacob AI, Goldberg PK, Bloom N, et al