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In November of 2023 the approval of a combo GLP-1/GIP for weight loss indications was announced

Monitoring and adjustment protocols should include: Weight and vital signs at each visit (initially monthly, then quarterly) Assessment of medication tolerance and adherence Evaluation of eating behaviors and physical activity Laboratory monitoring as outlined previously Reassessment of weight-related comorbidities Realistic expectations should be established through shared decision-making

At these levels, individuals may also experience drowsiness or even blackouts

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