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The segment is impelled by the broad use and proven efficacy of various injectable formulations, including dulaglutide (Trulicity), semaglutide (Ozempic, Wegovy), and liraglutide (Victoza, Saxenda) in managing type 2 diabetes and obesity

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Notably, genetically proxied agonists of GIPR, GLP-1R, and GCGR/GLP-1R all showed causal effects on lower levels of BMI, while the GIPR/GLP-1R agonist and GCGR/GIPR/GLP-1R agonist did not provide evidence of decreasing BMI, potentially attributed to the heterogeneity among variants (Table 2)