A 2.5 mg track has short direct data and real-world support for stable maintainers, but continuing tirzepatide has much stronger evidence than stopping. At week 112, stepping down to 5 mg preserved 16.6% weight loss versus 21.9% on the top dose and 9.9% on placebo
The headline finding: total lean mass declined by 10.9% over that period
78 (10), 1239412409 (2022) Alenezi, F., Armghan, A., Polat, K.: Wavelet transform based deep residual neural network and ReLU based extreme learning machine for skin lesion classification
Most patients experience mild, temporary nausea, constipation, or reduced appetite, which typically improve within weeks as your body adjusts