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Use gentle exfoliation, physical or enzymatic rather than acid-based, once weekly to clear accumulated dead cells

Recently, the microbiota-gut-brain axis has gained extensive attention as a channel for communication and physiological regulation ( Bacteria have recently been identified in the brains of AD patients, suggesting that the microbiota may be a contributing factor to related neuroinflammation (Yang et al., 2020)

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These research models are designed to evaluate biochemical pathway activity and cellular signaling responses , not therapeutic outcomes