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Mounjaro FDA Safety Label Change Ozempic (semaglutide) subcutaneous weekly injection FDA Approval Year: 2017 Ozempic FDA Safety Label Change Rybelsus (active ingredient: semaglutide) once-daily pills FDA Approval Year: 2019 Rybelsus FDA Safety Label Change Soliqua 100/33 (insulin glargine and lixisenatide) subcutaneous daily injection FDA Approval Year: 2016 Soliqua FDA Safety Label Change Trulicity (dulaglutide) subcutaneous weekly injection FDA Approval Year: 2014 Clinical trials reports of stomach problems (gastrointestinal effects) added

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BMJ 307(6899):295299 Tuomilehto J, Lindstrom J, Eriksson JG et al (2001) Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance

Hemoglobin A1c (HbA1c): Among 27 outcome estimates, 24 showed significant reductions in HbA1c