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Conversely, norepinephrine and -adrenergic agonists inhibit (84) and -adrenergic agonists stimulate (52, 182) GLP-1 secretion suggesting that sympathetic neural innervation of the gut is also important in the regulation of GLP-1 secretion

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The organizations seeing the greatest success are focusing on balanced strategies that combine thoughtful coverage design, clinical support, utilization management, and ongoing evaluation of outcomes