when was semaglutide discovered From Diabetes to Weight Loss Wonder: The History of Ozempic Started With a Lizard,

indicating the pathological role of soluble TNF- receptor-I in endometriosis [165]

Tirzepatide (Mounjaro) leads to about 20% of body weight lost after a little bit over a year according to the SURMOUNT trial: Semaglutide (Ozempic, Wegovy, Rybelsus) leads to about 15% of body weight lost after a bit over a year according to the STEP 1 trial: You can also look at a head to head comparison, the SURMOUNT-2 trial, which showed the tirzepatide was better than semaglutide at lowering blood sugar in diabetic patients: And clinically, at least in my experience, tirzepatide is way better tolerated than semaglutide

Overall, albumin significantly changed levels of 151 and 138 intracellular metabolites at 3 h and 24 h, respectively, and 49 exometabolites at 24 h (Fig

Thats the end game, he says