These differences help explain why GLP-1 drugs work best for people whose obesity is rooted in gut hormone dysfunction, while those with brain-based appetite signaling issues may respond better to older medications or drug combinations
Hu J, Zhang Y, Jiang X, Zhang H, Gao Z, Li Y, Fu R, Li L, Li J, Cui H, Gao N
Theres also some evidence for a few other nutrients that specifically affect GLP-1: Fiber : In rats and dogs, at least, dietary fiber increases GLP-1 production
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