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Certain people shouldn't take it: Pregnant or breastfeeding women People with a history of pancreatitis People with Type-1 diabetes People with an allergy to semaglutide (or any of its ingredients) People with Multiple Endocrine Neoplasia syndrome type 2 History of thyroid cancer Always consult a medical professional before taking semaglutide
That extra month of escalation gives the body more time to adapt and may contribute to tirzepatide's superior tolerability despite higher absolute doses
doi:10.1038/oby.2005.142
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