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Stopping Too Soon Some people stop treatment after a few weeks if they dont see results

This emphasizes the need for longitudinal and mechanistic studies that resolve the cause and consequence of the relationship between IR and depression

Keywords: Cardiovascular disease, Chronic kidney disease, Glucose-lowering therapy, Guidelines, Heart failure, Holistic care, Person-centred care, Social determinants of health, Type 2 diabetes mellitus, Weight management Introduction Type 2 diabetes is a chronic complex disease and management requires multifactorial behavioural and pharmacological treatments to prevent or delay complications and maintain quality of life (Fig

While these medications can help regulate appetite and support weight loss, sustainable success comes from pairing them with smart, supportive choices