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1 Among maintenance treatments available for COPD, currently only LABAs are available for nebulized delivery and hence there is a gap in therapy for COPD patients who may need a nebulized option for a LAMA, either as monotherapy or to be used in conjunction with a nebulized LABA

The general procedure followed in the laboratory for this type includes reconstitution with bacteriostatic or sterile water, storage of the lyophilized powder under cool and dark conditions, and storing the reconstituted solution under cold temperatures to avoid repetitive freeze-thaw cycles and light

2 School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

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