does semaglutide decrease inflammation Semaglutide: Double-edged Sword with Risks and Benefits Semaglutide reduced inflammation and oxidative

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: Wegovy an adjunct to diet and exercise to reduce body weight an maintain weight reduction to reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke) in adults with established cardiovascular disease and either obesity or overweight

Wegovy's approval is based on results from Part 1 of the ESSENCE trial, which involved around 800 patients treated with semaglutide or placebo on top of standard care and followed for 72 weeks

If 8mg weekly produces excellent results with minimal side effects, there may be no benefit to pushing to 12mg if doing so causes substantial discomfort