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Tuberculosis remains a public health threat despite an average decline in TB incidence because of the rise in comorbidities involving conditions such as diabetes and HIV

One study showed that GLP-1 protected pancreatic beta cells against glucosamine-induced cytotoxicity through suppressing AMPK activity, and subsequently led to recovery of the phosphorylation levels of P70S6K and S6RP and alleviate glucosamine-induced cell death 36

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This article shows that unimolecular GLP1/GIP co-agonism corrects obesity and glucose intolerance in obese rodents and non-human primates