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Cardiovascular and non- cardiovascular safety of dipeptidyl peptidase-4 inhibition: a meta- analysis of randomized controlled cardiovascular outcome trials

LY4101174 and LY4052031 are two next-generation Nectin-4-targeting ADCs that have demonstrated robust antitumor activity across a range of Nectin-4 expression levels and in a Nectin-4-MMAE ADC-resistant tumor model in the preclinical setting 185,186