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Media with no serum enabled stable co-cultures of iPSC-derived microglia and brain endothelial cells which respond appropriately to inflammatory stimuli, such as lipopolysaccharide (Bull et al., Induced Pluripotent Stem Cells Induced pluripotent stem cells have been used in multiple configurations: static transwell mono- or co-cultures (Stebbins et al., 2019) and monoculture microfluidic models (Faley et al., 2019) or with iPSC-derived neuron or pericyte (Jamieson et al., 2019

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Meta-analysis also demonstrated significant reductions in cardiovascular mortality, all-cause mortality, non-fatal myocardial infarction, non-fatal stroke, and hospitalisation for heart failure

It is important to stress that this picture is assembled from disparate in vitro and rodent experiments