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Vision loss and blindness Semaglutide is the active ingredient in Wegovy and its sister drugs, Ozempic and Rybelsus

When the clinical condition is critical and the potential benefits outweigh the risks, cautious use of the above agents may be considered

As for mortality, both SGLT-2 inhibitors and GLP-1RA are similar in reducing both total and CV deaths, but SGLT-2 inhibitors only are superior to DPP-4 inhibitors for both deaths, whereas GLP-1RA are superior to DPP-4 inhibitors for total death, but equal for CV death

What matters for this prediction is that concerns once dismissed as isolated complaints have evolved into one of the largest pharmaceutical litigations currently moving through the federal court system