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Early studies suggest that patients can achieve similar or even superior weight loss outcomes compared to GLP-1 monotherapy, with noticeable results within a few weeks to months

BMC Public Health 11(1):116 Ludvigsson JF, Almqvist C, Bonamy AKE et al (2016) Registers of the Swedish total population and their use in medical research

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Despite these potential risks, discontinuation rates due to the adverse impacts remain low, highlighting the tolerability and effectiveness of GLP-1 agonists for most clients